Original paper
JAML promotes CD8 and γδ T cell antitumor immunity and is a novel target for cancer immunotherapy
Abstract
T cells are critical mediators of antitumor immunity and a major target for cancer immunotherapy. Antibody blockade of inhibitory receptors such as PD-1 can partially restore the activity of tumor-infiltrating lymphocytes (TILs). However, the activation signals required to promote TIL responses are less well characterized. Here we show that the antitumor activity of CD8 and γδ TIL is supported by interactions between junctional adhesion...
Paper Details
Title
JAML promotes CD8 and γδ T cell antitumor immunity and is a novel target for cancer immunotherapy
Published Date
Aug 24, 2021
Volume
218
Issue
10
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Notes
History