Review paper
Interplay between extracellular matrix components and cellular and molecular mechanisms in kidney fibrosis
Abstract
Chronic kidney disease (CKD) is characterized by pathological accumulation of extracellular matrix (ECM) proteins in renal structures. Tubulointerstitial fibrosis is observed in glomerular diseases as well as in the regeneration failure of acute kidney injury (AKI). Therefore, finding antifibrotic therapies comprises an intensive research field in Nephrology. Nowadays, ECM is not only considered as a cellular scaffold, but also exerts important...
Paper Details
Title
Interplay between extracellular matrix components and cellular and molecular mechanisms in kidney fibrosis
Published Date
Aug 1, 2021
Journal
Volume
135
Issue
16
Pages
1999 - 2029
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