Randomized trial of vitamin D versus placebo supplementation on markers of systemic inflammation in hypertensive patients

Animal and cell models indicated that vitamin D modulates inflammatory activity, which is considered relevant in the pathogenesis of arterial hypertension and cardiovascular diseases. We therefore aimed to investigate the effect of vitamin D supplementation on systemic markers of inflammation in a cohort of hypertensive patients.The Styrian Vitamin D Hypertension Trial is a single-centre, double-blind, placebo-controlled study conducted from...