Review paper
Retrospective Case Series Analysis of RAF Family Alterations in Pancreatic Cancer: Real-World Outcomes From Targeted and Standard Therapies
Abstract
In pancreatic cancer (PC), the RAF family alterations define a rare subset of patients that may predict response to inhibition of the BRAF/MEK/ERK signaling pathway. A comprehensive understanding of the molecular and clinical characteristics of RAF-mutated PC may support future development of RAF-directed strategies.Clinical outcomes were assessed across a multi-institutional case series of 81 patients with RAF family-mutated PC. Mutational...
Paper Details
Title
Retrospective Case Series Analysis of RAF Family Alterations in Pancreatic Cancer: Real-World Outcomes From Targeted and Standard Therapies
Published Date
Nov 1, 2021
Journal
Issue
5
Pages
1325 - 1338
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