Hepatic Ischemia/Reperfusion Injury involves functional tryptase/PAR-2 signaling in liver sinusoidal endothelial cell population
Abstract
Mast cells (MCs) are tissue-resident effector cells that could be the earliest responder to release a unique, stimulus-specific set of mediators in hepatic ischemia–reperfusion (IR) injury However, how MCs function in the hepatic IR has remained a formidable challenge due to the substantial redundancy and functional diverse of these mediators. Tryptase is the main protease for degranulation of MCs and its receptor-protease-activated receptor 2...
Paper Details
Title
Hepatic Ischemia/Reperfusion Injury involves functional tryptase/PAR-2 signaling in liver sinusoidal endothelial cell population
Published Date
Nov 1, 2021
Volume
100
Pages
108052 - 108052
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