RETRACTED: Controlled brimonidine release from nanostructured lipid carriers-laden silicone contact lens to treat glaucoma

A novel brimonidine-loaded nanostructured lipid carriers (Br-NLCs)-laden silicone contact lenses were designed for control ocular delivery of brimonidine for effective treatment of glaucoma. The Br-NLCs were found to be spherical in shape with an average size of 100–140 nm and a zeta potential of −31.1–33.7 mV. Compared to conventional soaked contact lenses (Br-SM), Br-NLCs-laden contact lenses improved critical lens properties such as swelling,...