Serum HMGB1 level is correlated with serum I-FABP level in neonatal patients with necrotizing enterocolitis

This study aims to investigate clinical significance of HMGB1 in neonatal patients with necrotizing enterocolitis (NEC).This observational study enrolled a total of 106 stage II-III NEC neonatal patients, who were admitted in our hospital from March 2014 to March 2019. In addition, 99 suspected NEC patients and 200 healthy controls were included. The serum levels of HMGB1, I-FABP, and inflammatory factors CRP, IL-1β, IL-6 and TNF-α were...