Original paper
Antitumoral effects of dovitinib in triple-negative breast cancer are synergized by calcitriol in vivo and in vitro
Volume: 214, Pages: 105979 - 105979
Published: Nov 1, 2021
Abstract
Chemotherapy is a standard therapeutic option for triple-negative breast cancer (TNBC); however, its effectiveness is often compromised by drug-related toxicity and resistance development. Herein, we aimed to evaluate whether an improved antineoplastic effect could be achieved in vitro and in vivo in TNBC by combining dovitinib, a multi-kinase inhibitor, with calcitriol, a natural anticancer hormone. In vitro, cell proliferation and cell-cycle...
Paper Details
Title
Antitumoral effects of dovitinib in triple-negative breast cancer are synergized by calcitriol in vivo and in vitro
Published Date
Nov 1, 2021
Volume
214
Pages
105979 - 105979
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Notes
History