The feeding behaviour of Amyotrophic Lateral Sclerosis mouse models is modulated by the Ca2+‐activated KCa3.1 channels
Abstract
Amyotrophic lateral sclerosis (ALS) patients exhibit dysfunctional energy metabolism and weight loss, which is negatively correlated with survival, together with neuroinflammation. However, the possible contribution of neuroinflammation to deregulations of feeding behaviour in ALS has not been studied in detail. We here investigated if microglial KCa 3.1 is linked to hypothalamic neuroinflammation and affects feeding behaviours in ALS mouse...
Paper Details
Title
The feeding behaviour of Amyotrophic Lateral Sclerosis mouse models is modulated by the Ca2+‐activated KCa3.1 channels
Published Date
Oct 5, 2021
Volume
178
Issue
24
Pages
4891 - 4906
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