Analysis of High-Risk Factors Associated with the Progression of Subaneurysmal Aorta to Abdominal Aortic Aneurysm in Rural Area in China

Published on Aug 24, 2021in Clinical Interventions in Aging3.023
· DOI :10.2147/CIA.S321921
Zhao Wenjun , Wang Gang (Lanzhou University)+ 4 AuthorsXingjie Li1
Estimated H-index: 1
#1Ashfaque A. Memon (Lund University)H-Index: 19
#2Moncef ZarroukH-Index: 9
Last. Kristina Sundquist (Lund University)H-Index: 79
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AimsAbdominal aortic aneurysm is a life-threatening condition due to the risk of aneurysm growth and rupture. There are no approved diagnostic or prognostic biomarkers for abdominal aortic aneurysm...
13 CitationsSource
#1K. Thorbjørnsen (Uppsala University)H-Index: 3
#2Sverker Svensjö (Uppsala University)H-Index: 9
Last. Anders Wanhainen (Uppsala University)H-Index: 42
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AbstractBackground: The aims of this study were to determine the prevalence of screening-detected subaneurysmal aorta (SAA), i.e. an aortic diameter of 2.5–2.9 cm, its associated risk factors, and ...
6 CitationsSource
#1Jonathan Golledge (JCU: James Cook University)H-Index: 73
Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently, the only treatment for AAA is open or endovascular surgical repair. In most parts of the developed world, AAAs can be identified at an early stage as a result of incidental imaging and screening programmes. Randomized clinical trials have demonstrated that early elective surgical repair of these small AAAs is not beneficial, and an unmet clinical need exists to develop medical therapies for small AAAs th...
132 CitationsSource
#1Elsa Kobeissi (Imperial College London)H-Index: 5
#2Makoto Hibino (Imperial College London)H-Index: 2
Last. Dagfinn Aune (Imperial College London)H-Index: 58
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Abdominal aortic aneurysms (AAA) are fatal in 80% of the cases when ruptured. Hypertension has been considered a potential risk factor for AAA; but the findings from prospective cohort studies have not been entirely consistent, nor have they been summarised in a comprehensive meta-analysis. Our aim was to conduct a systematic review and meta-analysis of cohort studies of the association between blood pressure, hypertension and AAA to clarify the strength and shape of these associations. We searc...
27 CitationsSource
Editor's Choice – European Society for Vascular Surgery (ESVS) 2019 Clinical Practice Guidelines on the Management of Abdominal Aorto-iliac Artery Aneurysms
685 CitationsSource
#1Andrew Ying (Westmead Hospital)H-Index: 2
#2Eshan T. Affan (RPA: Royal Prince Alfred Hospital)H-Index: 2
Background Abdominal aortic aneurysms (AAA) can cause significant mortality when ruptured but are often undiagnosed before this time. Population screening of high-risk individuals and early intervention may mitigate AAA-related mortality. Large trials have demonstrated a mortality benefit for AAA screening, but adoption is not ubiquitous. This study sought to systematically review and consolidate the most recent randomized trial evidence on AAA screening in men and its cost-effectiveness. Method...
14 CitationsSource
#1Natzi Sakalihasan (University of Liège)H-Index: 31
#2Jean-Baptiste Michel (French Institute of Health and Medical Research)H-Index: 84
Last. Rebecka Hultgren (KI: Karolinska Institutet)H-Index: 21
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An abdominal aortic aneurysm (AAA) is a localized dilatation of the infrarenal aorta. AAA is a multifactorial disease, and genetic and environmental factors play a part; smoking, male sex and a positive family history are the most important risk factors, and AAA is most common in men >65 years of age. AAA results from changes in the aortic wall structure, including thinning of the media and adventitia due to the loss of vascular smooth muscle cells and degradation of the extracellular matrix. If...
102 CitationsSource
#1Candyce Hamel (Ottawa Hospital Research Institute)H-Index: 15
#2Mona Ghannad (Ottawa Hospital Research Institute)H-Index: 3
Last. Chantelle Garritty (University of Split)H-Index: 26
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Abstract Objective The objective of this review was to perform a rapid evidence summary to determine the prevalence of subaneurysmal aortic aneurysms, growth rates, and risk factors that modulate growth in average-risk men aged 65 years and older. Secondary objectives were to evaluate benefits and harms of lifelong ultrasound (US) surveillance and treatment outcomes for any large aneurysms that develop in the screened population. Methods We searched multiple databases (eg, Ovid MEDLINE, Embase C...
6 CitationsSource
#1Evan J. Zucker (Stanford University)H-Index: 11
#2Anand M. Prabhakar (Harvard University)H-Index: 16
Abdominal aortic aneurysms (AAAs) are a leading cause mortality and morbidity but often go undiagnosed until late stages unless imaging is performed. In 2005, the United States Preventive Services Task Force (USPSTF) for the first time recommended one-time ultrasound screening for elderly male smokers and selective screening in other populations. These guidelines were reaffirmed and updated in 2014; a proposal for potential further revisions is now in early planning stages. In this article, we r...
6 CitationsSource
#1M. F. Bath (NIHR: National Institute for Health Research)H-Index: 1
#2David Sidloff (NIHR: National Institute for Health Research)H-Index: 17
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15 CitationsSource
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