Epidemiology and risk-stratification of NAFLD-associated HCC
Abstract
Non-alcoholic fatty liver disease (NAFLD) is projected to become the leading cause of hepatocellular carcinoma (HCC) in many countries. Many risk factors for NAFLD are also independently associated with HCC, including obesity, diabetes, Hispanic ethnicity and genetic polymorphisms in PNPLA3, TM6SF2, GCKR, MBOAT7 and HSD17B13. Steatosis-related lipotoxicity and oxidative DNA damage can induce hepatocarcinogenesis. These factors may explain the...
Paper Details
Title
Epidemiology and risk-stratification of NAFLD-associated HCC
Published Date
Dec 1, 2021
Journal
Volume
75
Issue
6
Pages
1476 - 1484
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