Preface: Cardiorenal Considerations for Type 2 Diabetes—Time to Exit the Dark Ages

Type 2 diabetes is a cardiorenal metabolic disorder that involves both the microvasculature and the macrovasculature. Hyperglycemia is the major factor responsible for the microvascular complications (i.e., eye, kidney, and nerve damage), whereas insulin resistance and its associated components (e.g., hypertension, dyslipidemia, visceral adiposity, procoagulant state, and endothelial dysfunction) are the major risk factors for the macrovascular...