Impact of deleterious variants in other genes beyond BRCA1/2 detected in breast/ovarian and pancreatic cancer patients by NGS-based multi-gene panel testing: looking over the hedge

Volume: 6, Issue: 4, Pages: 100235 - 100235
Published: Aug 1, 2021
Abstract
Hereditary breast cancer (BC), ovarian cancer (OC), and pancreatic cancer (PC) are the major BRCA-associated tumours. However, some BRCA1/2-wild-type (wt) patients with a strong personal and/or family history of cancer need a further genetic testing through a multi-gene panel containing other high- and moderate-risk susceptibility genes.Our study was aimed to assess if some BC, OC, or PC patients should be offered multi-gene panel testing, based...
Paper Details
Title
Impact of deleterious variants in other genes beyond BRCA1/2 detected in breast/ovarian and pancreatic cancer patients by NGS-based multi-gene panel testing: looking over the hedge
DOI
Published Date
Aug 1, 2021
Journal
Volume
6
Issue
4
Pages
100235 - 100235
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