Original paper
NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer
Abstract
N-myc downstream-regulated gene 1 (NDRG1) is a key regulator that interacts with many classic tumor signaling pathways, including some molecules downstream of the epidermal growth factor receptor (EGFR). However, whether NDRG1 is involved in the mechanism of resistance to cetuximab (CTX), the first monoclonal antibody targeting the EGFR has not been reported. Here, we found that NDRG1 enhanced the sensitivity of CTX in colorectal cancer (CRC)...
Paper Details
Title
NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer
Published Date
Aug 12, 2021
Journal
Volume
40
Issue
41
Pages
5993 - 6006
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History