Effect of binder type and lubrication method on the binder efficacy for direct compression
Abstract
The effect of different binders for direct compression on tablet critical quality attributes was investigated. Dicalcium phosphate, lactose and microcrystalline cellulose were used as fillers and combined with ten binders (10, 20 and 30% w/w). Binder properties were linked to tensile strength via partial least square analysis. Tablets containing VA64F and PH105 exhibited the highest tensile strength which was linked to their compaction...
Paper Details
Title
Effect of binder type and lubrication method on the binder efficacy for direct compression
Published Date
Sep 1, 2021
Volume
607
Pages
120968 - 120968
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