Morphological features of breast cancer circulating tumor cells in blood after physical and biological type of isolation

Background Circulating tumor cells (CTCs) have become an important biomarker in breast cancer. Different isolation tech-niques based on their biological or physical features were established. Currently, the most widely used methods for visualization after their separation are based on immunofluorescent staining, which does not provide the information on the morphology. Materials and methods The aim of this study was to evaluate how two different...