Review paper
Understanding p53 tumour suppressor network
Abstract
The mutation of TP53 gene affects half of all human cancers, resulting in impairment of the regulation of several cellular functions, including cell cycle progression and cell death in response to genotoxic stress. In the recent years additional p53-mediated tumour suppression mechanisms have been described, questioning the contribution of its canonical pathway for tumour suppression. These include regulation of alternative cell death modalities...
Paper Details
Title
Understanding p53 tumour suppressor network
Published Date
Aug 6, 2021
Journal
Volume
16
Issue
1
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Notes
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