Systems pharmacology approach uncovers the therapeutic mechanism of medicarpin against scopolamine-induced memory loss

Medicarpin is a natural pterocarpan-type phytoalexin widely distributed in many traditional Chinese medicines, such as Astragali Radix. A previous study showed that Astragali Radix demonstrated promising protective effects in neurons. However, there is no reported study on the neuroprotective function and the underlying mechanism of Medicarpin. This study aimed to demonstrate the neuroprotective effect of Medicarpin on Alzheimer's disease (AD)...