Phytomedicine
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#1Yuting Huang (Tianjin University of Traditional Chinese Medicine)H-Index: 3
#2Kai Zhang (Tianjin University of Traditional Chinese Medicine)H-Index: 1
Last. Guanwei Fan (HNU: Huanggang Normal University)H-Index: 23
view all 9 authors...
Abstract null null Background null : Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous disease presenting a substantial challenge to clinicians. Currently, there is no safe and efficacious HFpEF treatment. In this study, we reported a standardized herbal medicinal product, QiShenYiQi (QSYQ), that can be used in the treatment of HFpEF. null null null Methods null : HFpEF mice were established by infusing a combination of Nω-nitro-L-arginine methyl ester (L-NAME) and feedin...
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#1Yu-Meng Zhang (Xuzhou Medical College)H-Index: 2
#2Ting Zheng (Xuzhou Medical College)H-Index: 1
Last. Yao-Wu Liu (Xuzhou Medical College)H-Index: 17
view all 7 authors...
Abstract null null Background null : A crosstalk exists between diabetes and Alzheimer's disease (AD), and diabetic encephalopathy displays AD-like disorders. Sarsasapogenin (Sar) has strong anti-inflammatory efficacy, showing neuroprotection and memory-enhancement effects. null null null Purpose null : This study aims to verify the ameliorative effects of Sar on diabetic encephalopathy in vivo and in vitro, and to clarify the mechanisms from attenuation of AD-like pathology. null null null Meth...
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#1Dongli Li (Guangzhou University of Chinese Medicine)H-Index: 4
#2Chuipu Cai (STU: Shantou University)H-Index: 1
Last. Shuhuan Fang (Guangzhou University of Chinese Medicine)H-Index: 14
view all 10 authors...
Abstract null null Background null Medicarpin is a natural pterocarpan-type phytoalexin widely distributed in many traditional Chinese medicines, such as Astragali Radix. A previous study showed that Astragali Radix demonstrated promising protective effects in neurons. However, there is no reported study on the neuroprotective function and the underlying mechanism of Medicarpin. null null null Purpose null This study aimed to demonstrate the neuroprotective effect of Medicarpin on Alzheimer's di...
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#1Xiao Xiao Wu (CUHK: The Chinese University of Hong Kong)
#2Wing-Sum Siu (CUHK: The Chinese University of Hong Kong)H-Index: 17
Last. Christopher W.K. Lam (MUST: Macau University of Science and Technology)H-Index: 82
view all 13 authors...
Abstract null null Background null Atopic dermatitis (AD) is a chronic relapsing inflammatory and pruritic skin disease, affecting 10-20% of the population worldwide. Paeonia suffruticosa Andrews (Paeoniaceae) (Cortex Moutan) and Mentha haplocalyx Briq. (Labiatae) (Herba Menthae) have shown beneficial effects on AD. Calendula officinalis L. (Asteraceae) is commonly used for treating skin rashes and wounds. null null null Purpose null In the present study, a three-herbs formula including Cortex M...
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#1Kaihui Zhang (Guangzhou University of Chinese Medicine)
#2Yu-Feng Yao (Guangzhou University of Chinese Medicine)H-Index: 3
Last. Chen-Chen Zhu (Guangzhou University of Chinese Medicine)H-Index: 11
view all 11 authors...
Abstract null null Background null : Rabdosia Serra, the dried aerial parts of Rabdosia serra (Maxim.) Hara (RS) from the Labiatae family, is a traditional Chinese herbal medicine called Xihuangcao. Although RS has been found to exert a therapeutic effect on cholestasis, the underlying molecular mechanism remains unclear. null null null Purpose null : This study was designed to investigate the pharmacological effect and mechanism of RS on cholestatic rats using metabolomics platform. null null n...
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#1İsa Taş (SNU: Sunchon National University)H-Index: 5
#2Mücahit Varlı (SNU: Sunchon National University)
Last. So-Yeon Park (SNU: Sunchon National University)H-Index: 7
view all 16 authors...
Abstract null null Background null Physciosporin (PHY) is one of the potent anticancer lichen compound. Recently, PHY was shown to suppress colorectal cancer cell proliferation, motility, and tumorigenesis through novel mechanisms of action. null null null Purpose null We investigated the effects of PHY on energy metabolism and tumorigenicity of the human breast cancer (BC) cells MCF-7 (estrogen and progesterone positive BC) and MDA-MB-231 (triple negative BC). null null null Methods null The an...
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#1Eu Leong Yong (NUS: National University of Singapore)H-Index: 39
#2Wei Fun Cheong (NUS: National University of Singapore)H-Index: 1
Last. Susan Logan (NUS: National University of Singapore)H-Index: 7
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BACKGROUND Fragility fractures due to menopausal osteoporosis are a major cause of morbidity and mortality. Osteoporotic medications have substantial side effects that limit long term use. HYPOTHESES Ingestion of a purified extract of Epimedium spp. (EP) is safe, can increase serum levels of prenylflavonoid metabolites, exert positive changes in bone specific alkaline phosphatase (BSAP), suppress of tumor necrosis factor receptor associated factor 6 (TRAF6) protein in osteoclast-precursor monocy...
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#1Chia-Hsuan Chou (CSMU: Chung Shan Medical University)H-Index: 3
#2Ko-Hsiu Lu (CSMU: Chung Shan Medical University)H-Index: 21
Last. Shun-Fa Yang (CSMU: Chung Shan Medical University)H-Index: 66
view all 6 authors...
Abstract null null Background null : Metastasis caused a decline in the 5-years survival rate of osteosarcoma. Therefore, developing new targeted therapeutics for osteosarcoma treatment is imperative. Dihydromyricetin (DHM) has several physiological functions: it counteracts inflammation, oxidation, and antitumor properties. However, the effects of DHM on osteosarcoma and its underlying mechanisms are still not well understood. null null null Purpose null : In this study, we investigated the ant...
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#1Wei Zou (Southern Medical University)H-Index: 1
#2Yaqian Dong (Southern Medical University)H-Index: 4
Last. Menghua Liu (Southern Medical University)H-Index: 17
view all 9 authors...
Abstract null null Background null : Nephrotic syndrome (NS) is a common nephropathy with a complex and diverse aetiology. Both Imperatae rhizoma and Hedyotis diffusa Willd. are herbs that are widely used as medicine and functional food. In traditional Chinese medicine theory, they are used as an herbal pair (HP) to treat inflammation-related diseases in the clinic, especially disorders of the kidney. null null null Purpose null : This study aimed to investigate the anti-inflammatory and hypolip...
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#1Chenxi Yang (NU: Nanjing University)H-Index: 2
#2Chenglin Song (NU: Nanjing University)
Last. Wen Lv
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Abstract null null Background null Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life-threatening diseases and could occur in severe COVID-19 patients. Re-Du-Ning injection (RDN) is a tradition Chinese medicine preparation which has been clinically used for treatment of respiratory diseases including COVID-19. null null null Purpose null To elucidate the potential mechanisms of RDN for the treatment of ALI. null null null Methods null Female C57BL/6J mice were used t...
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