Papers 4530
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#1Shashank M Patil (Jagadguru Sri Shivarathreeswara University)
#2Prithvi S. Shirahatti (Department of Biotechnology)H-Index: 5
Last. Nagendra Prasad M N (Sri Jayachamarajendra College of Engineering)
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Abstract Background Azadirachta indica A. Juss. is an Indian medicinal plant with innumerable pharmacological properties. Studies have proven that the phytochemicals from neem possess remarkable contraceptive abilities with limited knowledge on its mechanism of action. Purpose The present review aims to summarize the efficiency of A. indica treatment as a contraceptive. Methods The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines were used. Published scienti...
#1Xinmeng Chen (CUHK: The Chinese University of Hong Kong)H-Index: 1
#2Jiang Ma (CUHK: The Chinese University of Hong Kong)H-Index: 8
Last. Ge Lin (CUHK: The Chinese University of Hong Kong)H-Index: 39
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Abstract Background Pyrrolizidine alkaloids (PAs) are common phytotoxins. PA intoxication is reported to cause severe acute liver damage, typically known as hepatic sinusoidal obstruction syndrome (HSOS), but it remains obscure whether the acute liver damage may progress into chronic liver disease characterized by hepatic fibrosis. Purpose This study aims to characterize the biochemical markers of liver injury and histological features of regressive and progressive liver fibrosis, and to examine...
#1Li-feng Chen (Chinese PLA General Hospital)H-Index: 5
#2Hongzhen Jiang (Chinese PLA General Hospital)
Last. Xiaodong Ma (Chinese PLA General Hospital)
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Abstract Background Effective therapies are needed to prevent the secondary injury and poor prognosis associated with emergency craniotomy of traumatic brain injury (TBI). Hypothesis/Purpose The wound-healing medicine Yunnan Baiyao (YB) and Xingnaojing (XNJ) adjunct-therapy may improve the outcome of orthodox mono-therapy (OT). Study design Randomized controlled trial. Methods Eighty patients with moderate-to-severe TBI received emergency craniotomy (within 12 hours after TBI) at the Chinese PLA...
#1Mohamed ElbadawiH-Index: 4
#2Ramy M. AmmarH-Index: 1
Last. Thomas EfferthH-Index: 73
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#1Xiaohui Wang (Dalian Medical University)H-Index: 1
#2Lu Wang (Dalian Medical University)
Last. Qiang Meng (Dalian Medical University)H-Index: 21
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ABSTRACT Background Chemical liver injury is one of the main causes of acute liver failure and death. To date, however, treatment strategies for acute liver injury have been limited. Therefore, there is an urgent need to find new therapeutic targets and effective drugs. NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome is a complex of multiple proteins that has been shown to induce cell death under inflammatory and stress pathologic conditions and is thought to provide new targets...
#1Li Jun Yang (MUST: Macau University of Science and Technology)H-Index: 2
#2Rui Hong Chen (MUST: Macau University of Science and Technology)H-Index: 1
Last. Vincent Kam Wai Wong (MUST: Macau University of Science and Technology)H-Index: 24
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Abstract Background The outbreak of coronavirus (SARS-CoV-2) disease caused more than 100,000,000 people get infected and over 2,200,000 people being killed worldwide. However, the current developed vaccines or drugs may be not effective in preventing the pandemic of COVID-19 due to the mutations of coronavirus and the severe side effects of the newly developed vaccines. Chinese herbal medicines and their active components play important antiviral activities. Corilagin exhibited antiviral effect...
#1Jessica Gasparello (University of Ferrara)H-Index: 9
#2Elisabetta D'Aversa (University of Ferrara)H-Index: 5
Last. Roberto Gambari (University of Ferrara)H-Index: 52
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Abstract Background A key clinical feature of COVID-19 is a deep inflammatory state known as “cytokine storm” and characterized by high expression of several cytokines, chemokines and growth factors, including IL-6 and IL-8. A direct consequence of this inflammatory state in the lungs is the Acute Respiratory Distress Syndrome (ARDS), frequently observed in severe COVID-19 patients. Cytokine storm is associated with severe forms of COVID-19 and poor prognosis for COVID-19 patients. Sulforaphane ...
#1Jiaqi Zhang (Peking Union Medical College)H-Index: 3
#2Hui Che (Peking Union Medical College)H-Index: 1
Last. Xu-Dong Tang (Peking Union Medical College)H-Index: 7
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Abstract Background : Proton pump inhibitors (PPIs) play an important role in the treatment of nonerosive reflux disease (NERD), but their long-term and excessive uses have been associated with safety concerns. Chinese herbal medicine (CHM) has become a popular alternative treatment for this condition. Methods : A total of 204 patients were randomly assigned to the combination group or PPI group (1:1 ratio). They were given JianpiQinghua (JQ) granules (34.8 g) plus omeprazole (10 mg) plus dummy ...
#1Kanika Khanna (G.N.D.U.: Guru Nanak Dev University)H-Index: 8
#2Sukhmeen Kaur Kohli (G.N.D.U.: Guru Nanak Dev University)H-Index: 15
Last. Parvaiz Ahmad (KSU: King Saud University)H-Index: 34
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Abstract Current scenario depicts that world has been clenched by COVID-19 pandemic. Inevitably, public health and safety measures could be undertaken in order to dwindle the infection threat and mortality. Moreover, to overcome the global menace and drawing out world from moribund stage, there is an exigency for social distancing and quarantines. Since December, 2019, coronavirus, SARS-CoV-2 (COVID-19) have came into existence and up till now world is still in the state of shock.At this point o...
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Diabetes mellitus