Papers 4,785
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#1Lucas Nunes Santana (UFRPE: Federal Rural University of Pernambuco)
#2Lethicia Souza Tavares (UFRPE: Federal Rural University of Pernambuco)H-Index: 1
Last. José Vitor Lima-Filho (UFRPE: Federal Rural University of Pernambuco)H-Index: 13
view all 10 authors...
Abstract null null Background null : The lectin from Cratylia argentea (CFL) is able to modulate the immune system response and is thus a potential phytotherapeutic substance. null null null Hypothesis/Purpose null : In this study, we investigated the role of CFL on control of bacterial infection caused by Listeria monocytogenes, the causative agent of human listeriosis. null null null Study design null : Swiss mice were infected with L. monocytogenes and then treated with CFL. null null null Me...
#1Xiumin Jiang (SDUTCM: Shandong University of Traditional Chinese Medicine)
#2Yongxin Luo (GZUCM: Guangzhou University of Chinese Medicine)
Last. Lin Yao (SDUTCM: Shandong University of Traditional Chinese Medicine)
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Abstract null null Background null : The combination of antiarrhythmic drugs with traditional Chinese formulas are used treatments for the management of paroxysmal atrial fibrillation(PAF). However, the most effective treatment for PAF has yet to be been determined. A Bayesian network meta-analysis study was thus performed for comparing the relative efficacy and tolerability of different treatment alternatives. null null null Methods null : A comprehensive literature review of randomized control...
#1Wei-Jia Zhang (Sun Yat-sen University)H-Index: 5
#2Chang Peng (Sun Yat-sen University)H-Index: 1
Last. Meicun Yao (Sun Yat-sen University)H-Index: 16
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Abstract null null Background null Colorectal cancer (CRC) is a widespread cancer with high morbidity and mortality. Chemoresistance and metastasis are the current challenges for CRC treatment. Sanguisorba officinalis Linn. (called DiYu in Chinese, DY) is a Traditional Chinese medicine (TCM), which its root is long used as medicinal part. In our previous study, the aqueous extract of DY could inhibit the Wnt/β-catenin pathway and showed great antitumor effect against CRC. The Wnt/β-catenin pathw...
#1Yan Guo (ZJNU: Zhejiang Chinese Medical University)H-Index: 3
#2Jiehong Yang (ZJNU: Zhejiang Chinese Medical University)H-Index: 12
Last. Haitong Wan (ZJNU: Zhejiang Chinese Medical University)H-Index: 13
view all 8 authors...
Abstract null null Background null Pyroptosis is a pro-inflammatory cell death characterized by the formation of inflammasomes. Abnormal inflammation in brain microvascular endothelial cells (BMECs) has been correlated with ischemic stroke. Protocatechuic aldehyde (PCA) is a hydrophilic phenolic acid derived from the traditional Chinese herb Salvia miltiorrhiza with significant anti-inflammatory effects. However, the mechanism of PCA on BMEC pyroptosis under ischemic injury has been largely unex...
#1Ik-Soo LeeH-Index: 30
#2Chan-Sik KimH-Index: 24
Last. Jin Sook KimH-Index: 35
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A B S T R A C T null null Background: Moutan radicis cortex (MRC) and Cinnamomi ramulus (CR) are commonly used in eastern Asian traditional medicine to treat various diseases including cerebrovascular and cardiovascular, and have wide spectrum of pharmacological activities. However, the effect against laser-induced choroidal neovascularization (CNV) of extract of MRC and CR (1:1) (MRCCR) has not yet been studied. null Purpose: Our aim was to investigate the inhibitory effect of MRCCR on patholog...
#1Xiao-Juan Zhao (NU: Nanjing University)H-Index: 9
#2Li Chen (NU: Nanjing University)H-Index: 118
Last. Ling-Dong Kong (NU: Nanjing University)H-Index: 51
view all 8 authors...
#1Li Cai (Anhui Medical University)H-Index: 11
#2Pan Zong (Anhui Medical University)
Last. Rong Li (Anhui Medical University)H-Index: 12
view all 8 authors...
Abstract null null Background null 7-Hydroxycoumarin (7-HC) as a coumarin compound is widely found in Chinese herbs and exhibits diverse biological activities. Promoting cell apoptosis of fibroblast-like synoviocytes (FLS) is a meaningful strategy for rheumatoid arthritis (RA). Though the protective effect of 7-HC on RA experimental models has been reported, the specific mechanisms, especially the possible relationships of this effect to regulating FLS proliferation and apoptosis, still need cla...
#1Hongpeng Jiang (CUMS: Capital Medical University)
#2Qianqian YaoH-Index: 2
Last. Huiying Li (Civil Aviation Authority of Singapore)
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Abstract null null Background: Epidemiological and clinical evidence suggests that diabetes increases the risk of liver cancer. Although the co-occurrence of type 2 diabetes (T2D) and liver cancer is becoming more frequent, the underlying mechanisms remain unclear. Even though baicalin, extensively used in traditional Chinese medicine (TCM), can control T2D and inhibit liver cancer separately, minimal research is available regarding its possible effect on T2D-induced liver cancer. Thus, in the p...
#1Yuan Feng (SPU: Shenyang Pharmaceutical University)H-Index: 6
#2Yanwu Li (GZUCM: Guangzhou University of Chinese Medicine)H-Index: 6
Last. Ning Li (SPU: Shenyang Pharmaceutical University)H-Index: 30
view all 6 authors...
Abstract null null Background null The application/abuse of antibiotics can cause antibiotic-induced intestinal injury (AIJ), a typical clinical issue that disturbs intestinal homeostasis. However, the underlying post-transcriptional mechanism of AIJ remains unknown. Glycyrrhetinic acid (GA) is one of the main components of Glycyrrhiza uralensis Fisch. and Glycyrrhiza inflata Batalin (Fabaceae), and findings of our previous study showed that GA can maintain intestinal homeostasis post-transcript...
#1Yaseen Hussain (Soochow University)H-Index: 2
#2Haroon Khan (Abasyn University)H-Index: 37
Last. Waqas Alam (Abasyn University)
view all 5 authors...
Abstract null null Background null With growing global prevalence, cancer is a major cause of disease-related deaths. The understanding of the fundamental tumor pathology has contributed to the development of agents targeting oncogenic signaling pathways. Although these agents have increased survival for defined cancers, the therapeutic choices are still limited due to the development of drug resistance. CRISPR/Cas9 is a powerful new technology in cancer therapy by facilitating the identificatio...
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