Psychotic-like Experiences and Polygenic Liability in the Adolescent Brain Cognitive Development Study

Childhood psychotic-like experiences (PLEs) often precede the development of later severe psychopathology. This study examined whether childhood PLEs are associated with several psychopathology-related polygenic scores (PGSs) and additionally examined possible neural and behavioral mechanisms. Adolescent Brain Cognitive Development Study baseline data from children with European ancestry (n = 4650, ages 9–10 years, 46.8% female) were used to...