Telomeres: New players in immune-mediated inflammatory diseases?
Abstract
Telomeres are repetitive DNA sequences located at the ends of linear chromosomes that preserve the integrity and stability of the genome. Telomere dysfunctions due to short telomeres or altered telomere structures can ultimately lead to replicative cellular senescence and chromosomal instability, both mechanisms being hallmarks of ageing. Chronic inflammation, oxidative stress and finally telomere length (TL) dynamics have been shown to be...
Paper Details
Title
Telomeres: New players in immune-mediated inflammatory diseases?
Published Date
Sep 1, 2021
Journal
Volume
123
Pages
102699 - 102699
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Notes
History