APOL1, Sickle Cell Trait, and CKD in the Jackson Heart Study
Abstract
Rationale & ObjectiveApolipoprotein L1 (APOL1) high-risk variants are associated with an increased risk for chronic kidney disease (CKD) among African Americans. Less is known regarding the risk for the development of CKD and kidney failure (end-stage kidney disease [ESKD]) among African Americans with only 1 APOL1 risk variant or whether the risk is modified by sickle cell trait.Study DesignThe Jackson Heart Study is a community-based...
Paper Details
Title
APOL1, Sickle Cell Trait, and CKD in the Jackson Heart Study
Published Date
Nov 1, 2021
Journal
Volume
3
Issue
6
Pages
962 - 973.e1
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Notes
History