PARP inhibitors in gastric cancer: beacon of hope
Abstract
Defects in the DNA damage response (DDR) can lead to genome instability, producing mutations or aberrations that promote the development and progression of cancer. But it also confers such cells vulnerable to cell death when they inhibit DNA damage repair. Poly (ADP-ribose) polymerase (PARP) plays a central role in many cellular processes, including DNA repair, replication, and transcription. PARP induces the occurrence of poly...
Paper Details
Title
PARP inhibitors in gastric cancer: beacon of hope
Published Date
Jun 24, 2021
Volume
40
Issue
1
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