ROBO2 hampers malignant biological behavior and predicts a better prognosis in pancreatic adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a fatalmalignant cancer with extremely poor prognosis and high mortality. Genome wide studies show that Slit/Robo signaling pathway takes a major effect in the oncogenesis and progression of pancreatic cancer. However, the function and mechanism of ROBO2 in the development of PDAC remains unclear.In present study, we use Western blot and real-time polymerase chain reaction (RT-PCR) to detect the...