Scandinavian Journal of Gastroenterology
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#1Bodil RothH-Index: 16
#2Danielle Bernadette Schiro (Lund University)
Last. Bodil OhlssonH-Index: 41
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PURPOSE Peripheral autonomic neuropathy, including enteric neuropathy, may be subtle and unrecognized for several years. Diagnosis of enteric neuropathy demands complicated examinations such as full-thickness bowel biopsy. We hypothesized that knowledge about simultaneous occurrence of different types of neuropathy would lead to faster recognition and diagnosis of autonomic/enteric neuropathy. The aim of the present systematic review was to increase the awareness of disease groups causing autono...
#1Louise Ladebo (AAU: Aalborg University)H-Index: 2
#2Lars Vinter-Jensen (AAU: Aalborg University)H-Index: 14
Last. Anne Estrup Olesen (AAU: Aalborg University)H-Index: 21
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BACKGROUND Short bowel syndrome is a disorder with several complications such as malnutrition and failure of drug therapy. Treatment with opioids is needed in many patients, and oral medication is preferred. However, optimal dosing is a difficult task as current guidelines are based on an intact gastrointestinal tract. Hence, the aim of this explorative case study was to assess the pharmacokinetics of orally administered oxycodone in patients with short bowel syndrome. METHODS Six patients with ...
#1Ko Nakata (Gunma University)
#2Mathieu PiocheH-Index: 17
Last. Toshio Uraoka (Gunma University)H-Index: 29
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Background and aim null An injection solution is required to create a submucosal cushion (SMC) for safe endoscopic resection procedures. The aim of this preliminary animal study was to clarify the safety and efficacy of a novel fully synthetic and self-assembled peptide (FSSP) solution as a submucosal injection material (SMIM). null Method null To compare the submucosal-lifting properties, 0.3% FSSP, Eleview®, sodium hyaluronate acid solution (SHA) and normal saline (NS) were randomly injected u...
#1Li Xing (Hebei Medical University)H-Index: 1
#2Hai-Tao Lv (Hebei Medical University)H-Index: 2
Last. Wei Bian (Hebei Medical University)H-Index: 1
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PURPOSE To evaluate the effect of AMD3100 treatment to cholangiocarcinoma by analyzing the relationship between them, and provide experimental evidence for whether AMD3100 can become a clinical treatment drug for cholangiocarcinoma. MATERIALS AND METHODS Cholangiocarcinoma RBE cell lines were used in this study. MTT cell proliferation test was used for evaluating the effect of gemcitabine and AMD3100 to cell. CXCR4, N-cadherin, VEGF-C and MMP-9 were detect by RT-PCR and western. Transwell was us...
#1Ming Tan (OUH: Odense University Hospital)H-Index: 2
#2Klaus Brusgaard (University of Southern Denmark)H-Index: 27
Last. Maiken Thyregod Joergensen (OUH: Odense University Hospital)H-Index: 10
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Background null Familial Pancreatic Cancer (FPC) is responsible for up to 10% of all cases of pancreatic ductal adenocarcinoma (PDAC). Individuals predisposed for FPC have an estimated lifetime risk of 16-39% of developing PDAC. While heritability of PDAC has been estimated to be 36% in a Nordic twin study, no heritability estimate specific on FPC has been reported. null Methods null A national cohort of Danish families with predisposition for FPC is currently included in a screening program for...
#1Vendel Ailin Kristensen (Oslo University Hospital)H-Index: 2
#2Randi Opheim (University of Oslo)H-Index: 8
Last. Asle W. Medhus (Oslo University Hospital)H-Index: 14
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BACKGROUND AND AIM Modern treatment strategies for inflammatory bowel disease (IBD) are postulated to change the natural disease course. Inception cohort studies are the gold standard for investigating such changes. We have initiated a new population-based inception cohort study; Inflammatory bowel disease in South Eastern Norway III (IBSEN III). In this article, we describe the study protocol and baseline characteristics of the cohort. METHODS IBSEN III is an ongoing, population-based observati...
#1Sara Kolehmainen (UH: University of Helsinki)H-Index: 1
#2Tero Ylisaukko-oja (University of Oulu)H-Index: 4
Last. Taina Sipponen (UH: University of Helsinki)H-Index: 26
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Objectives null We set out to determine the reasons for serum vedolizumab (VDZ) trough concentration (TC) measurements in inflammatory bowel disease (IBD) patients and to evaluate treatment modifications after therapeutic drug measurement (TDM). We also evaluated the effect of increased dosing on patients' response to VDZ therapy. null Methods null We performed a retrospective cohort study of IBD patients who received VDZ therapy at Helsinki University Hospital and whose VDZ levels were measured...
BACKGROUND Prolongation of cecal intubation time (CIT) directly affects the comfort of the patient and the colonoscopist. In this study, the effectiveness of using an abdominal binder (AB) during colonoscopy on procedure time and colonoscopy outcomes was investigated. METHODS We conducted a parallel randomized double-blind sham-device-controlled study of patients who underwent elective outpatient colonoscopy between 1 May 2020, and 31 August 2020. Participants were randomly assigned to AB (n = 1...
#1Zhengwei Zha (Anhui Medical University)
#2Wenyue Wu (Anhui Medical University)H-Index: 1
Last. Derun Kong (Anhui Medical University)H-Index: 3
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To explore the impact of the screening interval and methods on cirrhosis-related hepatocellular carcinoma (HCC) detection and to analyse the clinical features and prognosis of HCC.We recruited 3000...
#1Cheng Ding (Peking Union Medical College Hospital)H-Index: 2
#2Yatong Li (Peking Union Medical College Hospital)H-Index: 5
Last. Menghua Dai (Peking Union Medical College Hospital)H-Index: 8
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Pancreatic ductal adenocarcinoma (PDAC) is a fatalmalignant cancer with extremely poor prognosis and high mortality. Genome wide studies show that Slit/Robo signaling pathway takes a major effect i...
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