Challenges facing pathologists evaluating PD‐L1 in head & neck squamous cell carcinoma

Volume: 50, Issue: 9, Pages: 864 - 873
Published: Jul 8, 2021
Abstract
Programmed death-ligand 1 (PD-L1) expression with combined positive score (CPS) ≥1 is required for administration of checkpoint inhibitor therapy in recurrent/metastatic head and neck squamous cell carcinoma (HNSCC). The 22C3 pharmDx Dako immunohistochemical assay is the one approved as companion diagnostic for pembrolizumab, but many laboratories work on other platforms and/or with other clones, and studies exploring the potential...
Paper Details
Title
Challenges facing pathologists evaluating PD‐L1 in head & neck squamous cell carcinoma
Published Date
Jul 8, 2021
Volume
50
Issue
9
Pages
864 - 873
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