Identifying a novel biological mechanism for alcohol addiction associated with circRNA networks acting as potential miRNA sponges
Abstract
Our lab and others have shown that chronic alcohol use leads to gene and miRNA expression changes across the mesocorticolimbic (MCL) system. Circular RNAs (circRNAs) are noncoding RNAs that form closed-loop structures and are reported to alter gene expression through miRNA sequestration, thus providing a potentially novel neurobiological mechanism for the development of alcohol dependence (AD). Genome-wide expression of circRNA was assessed in...
Paper Details
Title
Identifying a novel biological mechanism for alcohol addiction associated with circRNA networks acting as potential miRNA sponges
Published Date
Jun 23, 2021
Journal
Volume
26
Issue
6
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