Arecanut (Areca catechu L.) seed polyphenol improves osteoporosis via gut-serotonin mediated Wnt/β-catenin pathway in ovariectomized rats

Arecanut (Areca catechu L.) is one of the most important industrial crops in tropical Asia and parts of east Africa. However, the arecanut industry has suffered pandemic loss caused by negative reports such as carcinogenic effect. The healthy development of arecanut industry is of great significance. Our previous study found that arecanut (Areca catechu L.) seed polyphenol (ACP) can increase bone mass in ovariectomized rats which is closely...