Synergistic Effect of Bioactive Inorganic Fillers in Enhancing Properties of Dentin Adhesives—A Review

Published on Jun 30, 2021in Polymers3.426
· DOI :10.3390/POLYM13132169
Imran Farooq10
Estimated H-index: 10
(U of T: University of Toronto),
Saqib Ali7
Estimated H-index: 7
(UoD: University of Dammam)
+ 4 AuthorsFahim Vohra26
Estimated H-index: 26
(KSU: King Saud University)
Dentin adhesives (DAs) play a critical role in the clinical success of dental resin composite (DRC) restorations. A strong bond between the adhesive and dentin improves the longevity of the restoration, but it is strongly dependent on the various properties of DAs. The current review was aimed at summarizing the information present in the literature regarding the improvement of the properties of DAs noticed after the addition of bioactive inorganic fillers. From our search, we were able to find evidence of multiple bioactive inorganic fillers (bioactive glass, hydroxyapatite, amorphous calcium phosphate, graphene oxide, calcium chloride, zinc chloride, silica, and niobium pentoxide) in the literature that have been used to improve the different properties of DAs. These improvements can be seen in the form of improved hardness, higher modulus of elasticity, enhanced bond, flexural, and ultimate tensile strength, improved fracture toughness, reduced nanoleakage, remineralization of the adhesive-dentin interface, improved resin tag formation, greater radiopacity, antibacterial effect, and improved DC (observed for some fillers). Most of the studies dealing with the subject area are in vitro. Future in situ and in vivo studies are recommended to positively attest to the results of laboratory findings.
Figures & Tables
📖 Papers frequently viewed together
32 Citations
1 Citations
#1Aasem M Alhenaki (KSU: King Saud University)H-Index: 3
#2Esra A Attar (KAU: King Abdulaziz University)H-Index: 1
Last. Tariq Abduljabbar (KSU: King Saud University)H-Index: 22
view all 6 authors...
The objective of this study was to synthesize and assess unfilled and filled (silica nanoparticles) dentin adhesive polymer. Methods encompassing scanning electron microscopy (SEM)-namely, energy dispersive X-ray spectroscopy (EDX), micro-tensile bond strength (µTBS) test, Fourier transform infrared (FTIR), and micro-Raman spectroscopy-were utilized to investigate Si particles' shape and incorporation, dentin bond toughness, degree of conversion (DC), and adhesive-dentin interaction. The Si part...
3 CitationsSource
#1Hyun-Jung Kim (Kyung Hee University)H-Index: 7
#2Han Eul Bae (Kyung Hee University)H-Index: 1
Last. Duck-Su Kim (Kyung Hee University)H-Index: 13
view all 7 authors...
The effects of the incorporation of sodium-free bioactive glass into glass ionomer cement (GIC) on the demineralized dentin are studied. Four experimental groups with various amounts of BAG in GIC were considered: BG0 group: 0 wt% (control); BG5 group: 5 wt%; BG10 group: 10 wt%; BG20 group: 20 wt%. The GIC surface and GIC-approximated demineralized dentin surfaces were evaluated using field emission scanning electron microscopy (FE-SEM). X-ray diffraction (XRD) analysis was performed to evaluate...
1 CitationsSource
#1Melissa Tiskaya (QMUL: Queen Mary University of London)H-Index: 2
#2Saroash Shahid (QMUL: Queen Mary University of London)H-Index: 8
Last. Robert G. Hill (QMUL: Queen Mary University of London)H-Index: 62
view all 4 authors...
Abstract Objective In recent years, numerous studies have analyzed the role of bioactive glass (BAG) as remineralizing additives in dental restorative composites. This current review provides a critical analysis of the existing literature, particularly focusing on BAGs prepared via the melt-quench route that form an “apatite-like” phase when immersed in physiological-like solutions. Methods Online databases (Science Direct, PubMed and Google Scholar) were used to collect data published from 1962...
4 CitationsSource
#1Nuha Al-Harbi (KAU: King Abdulaziz University)H-Index: 2
#2Hiba MohammedH-Index: 6
Last. Manasa Nune (Manipal University)H-Index: 2
view all 11 authors...
Regenerative medicine is a field that aims to influence and improvise the processes of tissue repair and restoration and to assist the body to heal and recover. In the field of hard tissue regeneration, bio-inert materials are being predominantly used, and there is a necessity to use bioactive materials that can help in better tissue–implant interactions and facilitate the healing and regeneration process. One such bioactive material that is being focused upon and studied extensively in the past...
3 CitationsSource
#1Rana S Al-HamdanH-Index: 6
#2Basil AlmutairiH-Index: 3
Last. Tariq AbduljabbarH-Index: 22
view all 7 authors...
An experimental adhesive incorporated with different nano-hydroxyapatite (n-HA) particle concentrations was synthesized and analyzed for dentin interaction, micro-tensile bond strength (μTBS), and degree of conversion (DC). n-HA powder (5 wt % and 10 wt %) were added in adhesive to yield three groups; gp-1: control experimental adhesive (CEA, 0 wt % HA), gp-2: 5 wt % n-HA (HAA-5%), and gp-3: 10 wt % n-HA (HAA-10%). The morphology of n-HA spheres was evaluated using Scanning Electron Microscopy (...
5 CitationsSource
#1Abdullah Alshahrani (KSU: King Saud University)H-Index: 6
#2Mohammed S. Bin-Shuwaish (KSU: King Saud University)H-Index: 9
Last. Fahim Vohra (KSU: King Saud University)H-Index: 26
view all 9 authors...
Aim:The study aimed to assess graphene oxide (GO) adhesive and its dentin interaction using scanning electron microscopy (SEM), MicroRaman spectroscopy and Microtensile bond strength (μTBS).Materia...
4 CitationsSource
#1Gabriela de Souza Balbinot (UFRGS: Universidade Federal do Rio Grande do Sul)H-Index: 8
#2Vicente Castelo Branco Leitune (UFRGS: Universidade Federal do Rio Grande do Sul)H-Index: 19
Last. Fabrício Mezzomo Collares (UFRGS: Universidade Federal do Rio Grande do Sul)H-Index: 20
view all 4 authors...
Abstract Objective This study aims to analyze the addition of niobium silicate particles to dental adhesive resins and evaluate its physicomechanical and biological properties. Methods: The SiNb particles were produced by the sol-gel route and presented a mean particle size of 2.1 μm and a specific surface area of 616,96m2/g. An experimental adhesive resin was formulated with 66 wt% Bisphenol A-Glycidyl Methacrylate and 33 wt% Hydroxyethyl methacrylate with diphenyl(2,4,6-trimethyl benzoyl)phosp...
1 CitationsSource
#1Xiuzhi Fei (UMB: University of Maryland, Baltimore)H-Index: 1
#2Yuncong Li (Xi'an Jiaotong University)H-Index: 5
Last. Hockin H.K. Xu (University of Maryland Marlene and Stewart Greenebaum Cancer Center)H-Index: 89
view all 10 authors...
Abstract Objective Pit and fissure sealants with antibacterial and remineralization properties have broad application prospects in caries prevention. The objectives of this study were to: (1) develop a novel pit and fissure sealant containing CaF2 nanoparticles (nCaF2) and dimethylaminohexadecyl methacrylate (DMAHDM); and (2) investigate the effects of nCaF2 and DMAHDM on biofilm response and fluoride (F) ion release for the first time. Methods Helioseal F was used as a control. Bioactive sealan...
8 CitationsSource
#1Xingxing Bai (TUT: Taiyuan University of Technology)H-Index: 1
#2Chucheng Lin (CAS: Chinese Academy of Sciences)H-Index: 1
Last. Bin Tang (TUT: Taiyuan University of Technology)H-Index: 40
view all 7 authors...
Abstract Objective The purpose of this work was to explore the enhancement effect of zinc doped mesoporous silica nanoparticles (Zn-MSNs), which could form micromechanical interlocking with resin matrix and sustainably release Zn2+, on the mechanical and antibacterial properties of the dental resin composites. Methods Zn-MSNs were prepared by a sol–gel method, and characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and N2 adsorption/desorption. The mechani...
12 CitationsSource
: Nano-hydroxyapatite (nano-HA) is a material with multiple uses due to its biocompatibility and its resemblance to the nonorganic bone structure. It is used in various dental domains such as implantology, surgery, periodontology, esthetics and prevention. The aim of this study is to provide a wide understanding of nano-HA and to promote treatments based on nanomaterials in dentistry. A search in two data bases, Scopus, and PubMED, was conducted over a 5 years period. We chose a 5 years period b...
17 CitationsSource
Cited By0
#1Konstantina Roussou (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 1
#2Alexandros K. Nikolaidis (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 9
Last. Elisabeth A. Koulaouzidou (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 15
view all 0 authors...
Over the last years, diverse commercial resin-based composites have dominated as dental filling materials. The purpose of the present study was to determine organic and inorganic eluates from five restorative materials using GC/MS and ICP–OES and to compare the effect on cell survival of human gingival fibroblasts of a conventional and a bioactive resin. Five commercially available restorative materials were employed for this study: ActivaTM Bioactive Restorative, ENA HRi, Enamel plus HRi Biofun...