Blood Pressure Level Is Associated With Changes in Plasma Aβ1 –40 and Aβ1–42 Levels: A Cross-sectional Study Conducted in the Suburbs of Xi’an, China

Objectives : Amyloid-β (Aβ) deposition in the brain is the hallmark of Alzheimer’s disease (AD) pathology. Hypertension is a risk factor for AD, but the effects of hypertension on Aβ deposition are not fully determined. Considering peripheral Aβ closely relates to Aβ deposition in the brain, we investigated the relationships between blood pressure (BP) level and plasma Aβ concentrations. Methods : One-thousand and sixty-nine participants (age...