Qiumin Qu
Xi'an Jiaotong University
Internal medicineRural areaEndocrinologyGenotypeBlood lipidsCross-sectional studyNeuropsychologyUnivariate analysisLogistic regressionOdds ratioCognitionAlleleChemistryProspective cohort studyChinaAdverse effectAmyloid betaSleep deprivationDiseaseDementiaParkinson's diseaseLipoproteinSleep restrictionPopulationCognitive impairmentConfidence intervalApolipoprotein EMedicineGerontology
52Publications
8H-index
385Citations
Publications 51
Newest
#1Kee Hyung Park (Gachon University)H-Index: 16
#2YoungSoon Yang (SCH: Soonchunhyang University)H-Index: 13
Last. Jee Hyang Jeong (Ewha Womans University)H-Index: 17
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BACKGROUND AND PURPOSE The rate of donepezil discontinuation and the underlying reasons for discontinuation in Asian patients with Alzheimer's disease (AD) are currently unknown. We aimed to determine the treatment discontinuation rates in AD patients who had newly been prescribed donepezil in routine clinical practice in Asia. METHODS This 1-year observational study involved 38 institutions in seven Asian countries, and it evaluated 398 participants aged 50-90 years with a diagnosis of probable...
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#1Meilin She (Xi'an Jiaotong University)
#2Suhang Shang (Xi'an Jiaotong University)H-Index: 8
Last. Jin Wang (Xi'an Jiaotong University)H-Index: 5
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Objectives: Amyloid-β (Aβ) deposition in the brain is the hallmark of Alzheimer's disease (AD) pathology. Hypertension is a risk factor for AD, but the effects of hypertension on Aβ deposition are not fully determined. Considering peripheral Aβ closely relates to Aβ deposition in the brain, we investigated the relationships between blood pressure (BP) level and plasma Aβ concentrations. Methods: One-thousand and sixty-nine participants (age above 45) from a village in the suburbs of Xi'an, China...
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#1Longfei Jia (Capital Medical University)H-Index: 18
#2Fangyu Li (Capital Medical University)H-Index: 9
Last. Jianping JiaH-Index: 42
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Previous genome-wide association studies have identified dozens of susceptibility loci for sporadic Alzheimer's disease, but few of these loci have been validated in longitudinal cohorts. Establishing predictive models of Alzheimer's disease based on these novel variants is clinically important for verifying whether they have pathological functions and provide a useful tool for screening of disease risk. In the current study, we performed a two-stage genome-wide association study of 3913 patient...
1 CitationsSource
#2Shan WeiH-Index: 2
Last. Qiumin QuH-Index: 8
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Objective: Growing evidence suggests that sleep disturbance is a risk factor for Alzheimer's disease (AD). Amyloid-β (Aβ) deposition in the brain is a main pathophysiology of AD. Considering that peripheral Aβ level is associated with brain Aβ deposition, the present study investigated the relationship between sleep disturbance and plasma Aβ levels. Methods: This is a population-based cross-sectional study. A total of 1,459 participants from a village in the suburbs of Xi'an, China, were enrolle...
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#1Yao Gao (Xi'an Jiaotong University)
#2Shan Wei (Xi'an Jiaotong University)H-Index: 2
Last. Jin Wang (Xi'an Jiaotong University)H-Index: 5
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Objective: Growing evidence suggests that sleep disturbance is a risk factor for Alzheimer's disease (AD). Amyloid-β (Aβ) deposition in the brain is a main pathophysiology of AD. Considering that peripheral Aβ level is associated with brain Aβ deposition, the present study investigated the relationship between sleep disturbance and plasma Aβ levels. Methods: This is a population-based cross-sectional study. A total of 1,459 participants from a village in the suburbs of Xi'an, China, were enrolle...
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#1Jin Wang (Xi'an Jiaotong University)H-Index: 5
#2Xiao-Juan Guo (Xi'an Jiaotong University)H-Index: 1
Last. Qiumin Qu (Xi'an Jiaotong University)H-Index: 8
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BACKGROUND Vascular factors and mitochondria dysfunction contribute to the pathogenesis of Alzheimer's disease (AD). DL-3-n-butylphthalide (NBP) has an effect in protecting mitochondria and improving microcirculation. OBJECTIVE The aim was to investigate the effect of donepezil combined NBP therapy in patients with mild-moderate AD. METHODS It was a prospective cohort study. 92 mild-moderate AD patients were classified into the donepezil alone group (n = 43) or the donepezil combined NBP group (...
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#1Suhang Shang (Xi'an Jiaotong University)H-Index: 8
#2Binyan Zhang (Xi'an Jiaotong University)
Last. Qiumin Qu (Xi'an Jiaotong University)H-Index: 8
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#1Anqi Wang (Xi'an Jiaotong University)
#2Ling Gao (Xi'an Jiaotong University)H-Index: 3
Last. Qiumin Qu (Xi'an Jiaotong University)H-Index: 8
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#1Beiyu Zhao (Xi'an Jiaotong University)H-Index: 4
#2Qiumin Qu (Xi'an Jiaotong University)H-Index: 8
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#1Beiyu Zhao (Xi'an Jiaotong University)H-Index: 4
#2Chenyu Liu (Xi'an Jiaotong University)H-Index: 1
Last. Qiumin Qu (Xi'an Jiaotong University)H-Index: 8
view all 6 authors...
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