A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines

Volume: 24, Issue: 8, Pages: 1151 - 1162
Published: Jun 24, 2021
Abstract
Dendritic spines, the postsynaptic compartments of excitatory neurotransmission, have different shapes classified from 'stubby' to 'mushroom-like'. Whereas mushroom spines are essential for adult brain function, stubby spines disappear during brain maturation. It is still unclear whether and how they differ in protein composition. To address this, we combined electron microscopy and quantitative biochemistry with super-resolution microscopy to...
Paper Details
Title
A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines
Published Date
Jun 24, 2021
Volume
24
Issue
8
Pages
1151 - 1162
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