Linear and Branched Forms of Short Antimicrobial Peptide-IRK Inhibit Growth of Multi Drug Resistant Staphylococcus aureus Isolates from Mastitic Cow Milk

Antimicrobial peptides (AMPs) offer a novel alternative to present day antibiotics which are becoming ineffective due to development of resistance in microbes. In this study, a short synthetic β sheet forming antimicrobial peptide-IRK (IRIKIRIK) was synthesized and we studied the effect of multimerization of peptides on its antimicrobial activity. The activity of linear, dimeric and tetrameric forms of IRK peptide was evaluated against reference...