Linear and Branched Forms of Short Antimicrobial Peptide-IRK Inhibit Growth of Multi Drug Resistant Staphylococcus aureus Isolates from Mastitic Cow Milk

Published on Sep 1, 2021in International Journal of Peptide Research and Therapeutics1.5
· DOI :10.1007/S10989-021-10243-7
Purnima Gogoi1
Estimated H-index: 1
,
Sameer Shrivastava8
Estimated H-index: 8
+ 3 AuthorsGyanendra Kumar Gaur7
Estimated H-index: 7
Source
Abstract
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The extensive use of antibiotics in medical, as well as in veterinary practices has led to the development of antibiotic resistance which is of increasing global concern. The so called “superbugs” or the multi-drug resistant bacteria have made the present day antibiotics less effective. Therefore, search of an alternative is the need of hour, and for which antimicrobial peptides (AMPs) could be a good approach. AMPs are relatively short (12 to 100 amino acids), amphipathic peptides isolated from...
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The current study was conducted to isolate and identify multidrug-resistant Staphylococcus aureus (MDR-SA) from mastitis milk samples and to determine their antimicrobial susceptibility pattern. A total of 48 bovine mastitis (BM) milk samples were collected from different parts of the Rangpur division, Bangladesh. After the collection of milk samples, mastitis was confirmed using the California mastitis test. Isolation and identification of Staphylococcus aureus were performed using conventional...
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ABSTRACT Staphylococcus aureus is one of the major pathogens causing mastitis in dairy herds. The colonization of dairy cows and subsequent contamination of raw milk by S. aureus, especially strains exhibiting multidrug resistance and biofilm-forming and toxin-producing abilities, remains an important issue for both dairy farmers and public health. In this study, we investigated the prevalence, antimicrobial susceptibility, biofilm formation, and genetic diversity of S. aureus from subclinical b...
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