GCMS profiling and in silico screening of alpha-amylase inhibitors in traditional pigmented rice varieties (Oryza sativa Linn) of Tamil Nadu

Alpha-amylase inhibitors are oral antidiabetic drugs known for inhibiting the alpha-amylase enzyme, which carries out starch hydrolysis, enabling its assimilation in the intestine. However, these drugs can cause several adverse side effects. The present study evaluated the alpha-amylase inhibitory potential of traditional pigmented rice bran crude extracts. This was accomplished through GC-MS profiling of the metabolites contained in the...