Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

Volume: 12, Issue: 1, Pages: 3417 - 3417
Published: Jun 7, 2021
Abstract
Genetic discoveries of Alzheimer’s disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical trials. We first perform a large genetic association study by merging all available case-control datasets and by-proxy study results (discovery n = 409,435 and validation size n = 58,190). Here, we add six variants associated...
Paper Details
Title
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
Published Date
Jun 7, 2021
Volume
12
Issue
1
Pages
3417 - 3417
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