Review paper
NRAS mutant melanoma: Towards better therapies
Abstract
Genetic alterations affecting RAS proteins are commonly found in human cancers. Roughly a fourth of melanoma patients carry activating NRAS mutations, rendering this malignancy particularly challenging to treat. Although the development of targeted as well as immunotherapies led to a substantial improvement in the overall survival of non-NRASmut melanoma patients (e.g. BRAFmut), patients with NRASmut melanomas have an overall poorer prognosis...
Paper Details
Title
NRAS mutant melanoma: Towards better therapies
Published Date
Sep 1, 2021
Journal
Volume
99
Pages
102238 - 102238
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