Altered canalicular remodeling associated with femur fracture in mice

We previously showed that femur fracture in mice caused a reduction in bone volume at distant skeletal sites within 2 weeks post‐fracture. Osteocytes also have the ability to remodel their surrounding bone matrix through perilacunar/canalicular remodeling (PLR). If PLR is altered systemically following fracture, this could affect bone mechanical properties and increase fracture risk at all skeletal sites. In this study, we investigated whether...