Actin-based force generation and cell adhesion in tissue morphogenesis

Volume: 31, Issue: 10, Pages: R667 - R680
Published: May 1, 2021
Abstract
The generation of organismal form - morphogenesis - arises from forces produced at the cellular level. In animal cells, much of this force is produced by the actin cytoskeleton. Here, we review how mechanisms of actin-based force generation are deployed during animal morphogenesis to sculpt organs and organisms. Furthermore, we consider how cytoskeletal forces are coupled through cell adhesions to propagate across tissues, and discuss cases...
Paper Details
Title
Actin-based force generation and cell adhesion in tissue morphogenesis
Published Date
May 1, 2021
Volume
31
Issue
10
Pages
R667 - R680
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