Original paper
Stimulation of toll‐like receptor pathways by burn eschar tissue as a possible mechanism for hypertrophic scarring
Abstract
Hypertrophic scars (HTS) are a common complication following burn injuries with prolonged inflammation. They do not respond well to current treatment options including mechanical, biomolecular and surgical therapies. Toll-like receptor (TLR) 2 and 4 respond to microbes and damaged endogenous ligands to trigger pro-inflammatory pathways, and they are expressed more in HTS fibroblasts compared to normal skin fibroblasts. TLR2 responds to microbial...
Paper Details
Title
Stimulation of toll‐like receptor pathways by burn eschar tissue as a possible mechanism for hypertrophic scarring
Published Date
May 27, 2021
Volume
29
Issue
5
Pages
810 - 819
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Notes
History