Review paper
The Role of the Mineralocorticoid Receptor and Mineralocorticoid Receptor–Directed Therapies in Heart Failure
Abstract
Mineralocorticoid receptor (MR) antagonists (MRA), also referred to as aldosterone blockers, are now well-recognized for their clinical benefit in patients who have heart failure (HF) with reduced ejection fraction (HFrEF). Recent studies have also shown MRA can improve outcomes in patients with HFpEF, where the ejection fraction is preserved but left ventricular filling is reduced. While the MR is a steroid hormone receptor best known for...
Paper Details
Title
The Role of the Mineralocorticoid Receptor and Mineralocorticoid Receptor–Directed Therapies in Heart Failure
Published Date
May 29, 2021
Journal
Volume
162
Issue
11
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