Targeting fibroblast growth factor receptors to combat aggressive ependymoma
Abstract
Ependymomas (EPN) are central nervous system tumors comprising both aggressive and more benign molecular subtypes. However, therapy of the high-risk subtypes posterior fossa group A (PF-A) and supratentorial RELA-fusion positive (ST-RELA) is limited to gross total resection and radiotherapy, as effective systemic treatment concepts are still lacking. We have recently described fibroblast growth factor receptors 1 and 3 ( FGFR1/FGFR3 ) as...
Paper Details
Title
Targeting fibroblast growth factor receptors to combat aggressive ependymoma
Published Date
May 27, 2021
Journal
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History