Paeonol Induces Protective Autophagy in Retinal Photoreceptor Cells

Background: Retinal photoreceptor (RP) cells are widely involved in retina-related diseases, and oxidative stress plays a critical role in retinal secondary damage. Herein, we investigated the effectiveness and potential mechanisms of autophagy of paeonol (Pae) in terms of oxidation resistance. Methods: The animal model was induced by light damage (LD) in vivo , whereas the in vitro model was established by H 2 O 2 stimulation. The effectiveness...