Rebalancing expression of HMGB1 redox isoforms to counteract muscular dystrophy
Abstract
Muscular dystrophies (MDs) are a group of genetic diseases characterized by progressive muscle wasting associated to oxidative stress and persistent inflammation. It is essential to deepen our knowledge on the mechanism connecting these two processes because current treatments for MDs have limited efficacy and/or are associated with side effects. Here, we identified the alarmin high-mobility group box 1 (HMGB1) as a functional link between...
Paper Details
Title
Rebalancing expression of HMGB1 redox isoforms to counteract muscular dystrophy
Published Date
Jun 2, 2021
Volume
13
Issue
596
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