Applications of fluorine to the construction of bioisosteric elements for the purposes of novel drug discovery
Volume: 16, Issue: 11, Pages: 1261 - 1286
Published: Jun 10, 2021
Abstract
Introduction There continues to be an exponential rise in the number of small molecule drugs that contain either a fluorine atom or a fluorinated fragment. While the unique properties of fluorine enable the precise modulation of a molecule’s physicochemical properties, strategic bioisosteric replacement of fragments with fluorinated moieties represents an area of significant growth.Areas covered This review discusses the strategic employment of...
Paper Details
Title
Applications of fluorine to the construction of bioisosteric elements for the purposes of novel drug discovery
Published Date
Jun 10, 2021
Volume
16
Issue
11
Pages
1261 - 1286
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History