Fast-Trk(B)ing the mechanism of antidepressants
Abstract
The mechanism by which antidepressants elicit clinical improvements has proven elusive. In a recent publication in Cell, Casarotto et al., 2021Casarotto P.C. Girych M. Fred S.M. Kovaleva V. Moliner R. Enkavi G. Biojone C. Cannarozzo C. Sahu M.P. Kaurinkoski K. et al.Antidepressant drugs act by directly binding to TRKB neurotrophin receptors.Cell. 2021; 184: 1299-1313.e19https://doi.org/10.1016/j.cell.2021.01.034Abstract Full Text Full Text PDF...
Paper Details
Title
Fast-Trk(B)ing the mechanism of antidepressants
Published Date
May 1, 2021
Journal
Volume
109
Issue
10
Pages
1593 - 1595
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