The Case | A 38-year-old man with hydronephrosis

A 38-year-old man was referred to the department of nephrology for the evaluation of bilateral hydronephrosis. The patient had a history of polyuria since childhood for which he had been using a desmopressin nasal spray for >20 years without a clear diagnosis. On physical examination, he had no costovertebral angle tenderness or peripheral edema. The family history revealed that his grandmother, father, aunt, uncle, and sister had similar...