Protein synthesis inhibitor omacetaxine is effective against hepatocellular carcinoma
Abstract
Hepatocellular carcinoma (HCC) is the sixth most common and the fourth most deadly cancer worldwide. The development cost of new therapeutics is a major limitation in patient outcomes. Importantly, there is a paucity of preclinical HCC models in which to test new small molecules. Herein, we implemented potentially novel patient-derived organoid (PDO) and patient-derived xenografts (PDX) strategies for high-throughput drug screening. Omacetaxine,...
Paper Details
Title
Protein synthesis inhibitor omacetaxine is effective against hepatocellular carcinoma
Published Date
Jun 22, 2021
Journal
Volume
6
Issue
12
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