The language of chromatin modification in human cancers
Abstract
The genetic information of human cells is stored in the context of chromatin, which is subjected to DNA methylation and various histone modifications. Such a ‘language’ of chromatin modification constitutes a fundamental means of gene and (epi)genome regulation, underlying a myriad of cellular and developmental processes. In recent years, mounting evidence has demonstrated that miswriting, misreading or mis-erasing of the modification language...
Paper Details
Title
The language of chromatin modification in human cancers
Published Date
May 17, 2021
Journal
Volume
21
Issue
7
Pages
413 - 430
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