Single-Cell Transcriptomics Reveals Endothelial Plasticity During Diabetic Atherogenesis
Abstract
Atherosclerosis is the leading cause of cardiovascular diseases, which is also the primary cause of mortality among diabetic patients. Endothelial cell (EC) dysfunction is a critical early step in the development of atherosclerosis and aggravated in the presence of concurrent diabetes. Although the heterogeneity of the organ-specific ECs has been systematically analyzed at the single-cell level in healthy conditions, their transcriptomic changes...
Paper Details
Title
Single-Cell Transcriptomics Reveals Endothelial Plasticity During Diabetic Atherogenesis
Published Date
May 19, 2021
Volume
9
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