Sclerosing Epithelioid Mesenchymal Neoplasm of the Pancreas

To the Editor: Sclerosing epithelioid mesenchymal neoplasm (SEMN) of the pancreas was first reported as a new entity by Basturk et al1 in 2020. It occurs most frequently in young women and has a favorable prognosis. Microscopically, it has a tendency to form “geographic” and “slit-like” patterns of enmeshed tumor cells. Immunohistochemically, the tumor has a mesenchymal nature, and molecularly, it demonstrates no recurrent somatic mutations but...